The Answers to the image quiz from May 21, 2012:
A. Diffuse proliferative
glomerulonephritis: higher power EM showing details of
the glomerular capillary wall with subepithelial humps (A2-white asterisks), and a large, confluent subendothelial electron dense deposit (A1-arrows).
B. Diffuse proliferative
glomerulonephritis: This electron micrograph shows a subepithelial "hump“ (B1- D) and a portion of one neutrophil (PMN) in the lumen. Notice the close contact between the
endothelial cell and the inflammatory cell. There is prominent effacement of the foot processes of the
epithelium overlying the deposit, with dense condensation of microfilaments in
the cytoplasm in this area.
C. Mesangioproliferative glomerulonephritis (e.g., IgA nephropathy). There
is preservation of the peripheral capillary wall. The mesangium shows large electron
dense deposits (C.1-arrows).
The Questions
Name the deposits is the purpose of the quiz. You have 3 pictures, A, B, and C. The deposits are labelled by numbers in red. Name the type/location of deposit (e.g., subsendothelial versus mesangial deposit).
A1, A2, B1, C1
