A) Nodular glomerular disease of diabetic nephropathy
B) Focal segmental glomerulosclerosis
C) IgA nephropathy
D) Membranoproliferative glomerulonephritis
E) Membranous glomerulonephropathy
___________
The answer to Image Quiz from November 5, 2011 is D.) Focal segmental glomerulosclerosis
The image shows a patient with:
A.) IgA nephropathy
B.) Membranoproliferative glomerulonephritis
C.) Membranous glomerulopathy
D.) Focal segmental glomerulosclerosis
E.) Minimal change disease
Explanation
The characteristic lesion in FSGS is segmental solidification of the glomerular tuft, usually in the perihilar region and sometimes in the peripheral areas, including the tubular pole. In affected glomeruli, capillaries are segmentally obliterated by accumulation of acellular matrix and hyaline deposits, along with adhesion to the Bowman capsule.
