Sunday, September 4, 2011

IMAGE QUIZ

This is a patient with edema and an albumin creatinine ratio of 5.2. What cast is this?

Answer for August's images quiz: B. Cystine crystals

  • Cystine crystals are usually hexagonal, translucent, white.
  • Cystinuria is an autosomal recessive disorder caused by mutations in the SLC3A1 and SLC7A9 genes. These genes encode two parts of a transporter protein in the kidneys.
  • Under normal circumstances, this protein allows certain amino acids, including cysteine, to be reabsorbed into the blood from the filtered fluid that will become urine.
  • As the levels of cystine in the urine increase, the crystals typical of cystinuria are able to form, resulting in kidney stones.